Date and Time: 10th August 2012 (Friday), 10:00 AM
Venue: HG01, Ho Yin Convention Centre, University of Macau
Abstract
I present recent progress of implantable biomedical devices based on CMOS technologies developed in our laboratory. First, I introduce retinal prosthesis devices, which are implanted in the retina and electrically stimulate retinal cells to partially restore vision for blind patient suffered from retinitis pigmentosa (RP) and age-related macular degeneration (AMD). To realize clear vision, over 1000 stimulus points are required. We are developing a retinal prosthesis device with large number of electrodes by introducing CMOS technologies. We have successfully demonstrated that a CMOS-based stimulator implanted in a rabbit eye can stimulate the retinal cells. Next, I show an implantable device into a mouse brain to measure in vivo imaging of fluorescence in real-time. The device is based on a dedicated CMOS image sensor with UV-LEDs to excite fluorescence, which can be detected with the image sensor. We have successfully demonstrated real-time in vivo protease imaging inside the mouse hippocampus. Finally I address the future direction of the implantable biomedical CMOS devices.
Biography
Jun Ohta was born in Gifu, Japan in 1958. He received the B.E., M.E., and Dr. Eng. degrees in applied physics, all from the University of Tokyo, Japan, in 1981, 1983, and 1992, respectively.
In 1983, he joined Mitsubishi Electric Corporation, Hyogo, Japan, where he engaged in the research on optoelectronic integrated circuits, optical neural networks, and artificial retina chips. From 1992 to 1993, he was a Visiting Researcher in Optoelectronics Computing Systems Center, University of Colorado at Boulder, where he engaged in the research on smart CMOS sensors. In 1998, he joined Graduate School of Materials Science, Nara Institute of Science and Technology (NAIST), Nara, Japan as Associate Professor. He was appointed as Professor in 2004. His current research interests are vision chips, CMOS image sensors, retinal prosthesis, biomedical-photonic LSIs, integrated photonic devices.